IN VITRO ANTHELMINTIC ACTIVITY OF AZADIRACHTA INDICA (NEEM) AND MELIA AZEDARACH (BAKAIN) ESSENTIAL OILS AND THEIR SILVER NANOPARTICLES AGAINST HAEMONCHUS CONTORTUS

Synthetic drugs are mostly used for the control and prevention of parasitic ailments in ruminants. However, resource-poor people developing countries use herbal medicines to treat their animals. Ethnoveterinary medicine along with its huge beneficial effects also prevents emergence drug resistance. Therefore, it is necessary validate efficacy these medicinal plants scientifically future endoparasitic infections. Thus, this study aims evaluate vitrobanthelmintic two indigenous plant extracts namely Azadirachta (A.) indica Melia (M.) azedarach. The essential oils (EOs) silver nanoparticles (AgNPs) were obtained from seeds leaves by hydro-distillation centrifugation techniques. Their studied performing egg hatch assay (EHA) adult motility (AMA) against Haemonchus contortus. results analyzed using Probit analysis. In our study, EO NP M. azedarachbresulted a 50% reduction hatching EHA at 0.209 0.204µL/L, A. 0.456 0.184µL/L respectively. Essential AgNPs azedarach found be effective AMA 0.036, 0.362, 0.305, 0.032µL/L Further studies still required know more about effectiveness different stages.